I was having crazy problems/issues with Visual Studio 2010 and multiple monitors. Intelisense would not show up on the secondary monitor. Code would suddenly disappear. Detaching a window on the main monitor and then moving it to the secondary monitor would cause the detached window to permanently disappear.
It was getting to be very annoying.
Found a fix, which looks to me that the cause has something to do with VS2010 and support for my laptop’s display adapter.
Go to Tools –> Options –> General. Disable hardware acceleration.